The University of California Research eXchange (UC ReX) Data Explorer, is a secure,
web based system that enables UC investigators to identify potential research study
cohorts and at the five UC medical centers*. Users can conduct interactive searches
of data derived from patient care activities at Davis, Irvine, Los Angeles, San Diego
and San Francisco. The output of each query is a numeric count of cohorts by site
that match the criteria identified in the query. The numeric counts can help assess the
feasibility of a study or hypotheses by identifying whether there are sufficient prospective
subjects within the UC system. Quality administrators and analysts can use counts for
quality initiatives.

Data Explorer data are de-identified data-sets extracted from each institution’s clinical
data warehouse. Integrating Biology and the Bedside (i2b2), technology developed by
a NIH funded collaborative, allows clinical records to be transformed into a common
data representation and stored in dedicated data repositories at each institution.

Each data repository is federated by an additional software system called Shared Health Research Informatics Network (SHRINE), a Harvard Catalyst technology that sends a
query to the repository at each participating site and then displays the count results
returned from each. The Data Explorer user interface allows users to directly interact
with the system, creating queries that search for specific patient characteristics. A user
who wants to identify non-Hispanic, African American patients having diagnoses of both
type 2 diabetes and hypertension can use UC Data Explorer to obtain counts of potential subjects at each site. Based on these results, one can decide which of the UC medical
centers to approach for study collaboration or review of quality outcomes across
multiple sites.
Copyright © 2013 The Regents of the University of California.